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THIRD -COUNTRY ECONOMIC UNION AS PHOSPHYSIDE 3 -KINNING INSTALLATIONS
THIRD -COUNTRY ECONOMIC UNION AS PHOSPHYSIDE 3 -KINNING INSTALLATIONS
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机译：第三国经济联盟作为农药3-固定安装
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摘要
A type I compound: (I) or its medically acceptable salt,where: W is O,N -H,N -(C1 -C10 alkyl) or S; each X whether CH or N; R1 is 5 -membered to 7 -membered saturated or unsaturated,optional sub -circuit containing at least one alternate selected from N or O; R2 is LY; each L is a direct link,C1 -C10 alkylene,C2 -C10 alkenyl or C2 -C10 alkenyl,Y is a voluntary subordinate;a non -aromatic 5 -12 bridge or spiral design heterocycle containing up to four heterocycles selected from N or O,and each R3 irrespective of its H,C1 -C10 alkyl,horse,C1 -C10 alkyl fluoride,O -C1 -C10 alkyl,NH -C1 -C10 alkyl,S -C1 -C10 alkyl,O -fluoride C1 -C10 alkyl,N -Acyl,NH -C (O)-NH -C1 -C10 alkyl,C (O)-NH -C1 -C10 alkyl,aryl or ether,are useful as class A enzyme inhibitors of 3 -kinase phosphokinitis,RI3K -p110d,and therefore potentially useful in the treatment of cancer,Immune system disorders and inflammatory diseases.
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