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Compounds, preparation procedures, pharmaceutical ingredients, use of compounds, and treatment of mental disorders and/or sleep disorders

机译：化合物，制备程序，药物成分，化合物的使用以及精神障碍和/或睡眠障碍的治疗

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Generally speaking, current inventions are related to new and invented benzimide derivatives with drug activity.Surprisingly, they have high affinity with MT1 and MT2 receivers of melamine and low affinity with enzymes of CYP450, especially CYP1A2.It also describes new and innovative synthetic pathways for these compounds.Drug components of these compounds used in the treatment of individuals with mental disorders and/or sleep disorders associated with themCough receptors (especially depression, anxiety, and ircadian cycle disorders) plus component production procedures.

机译：一般而言，当前的发明涉及具有药物活性的新的和发明的苯甲酰亚胺衍生物，令人惊讶的是，它们与三聚氰胺的MT1和MT2受体具有高亲和力，与CYP450的酶特别是CYP1A2的亲和力低，还描述了新的和创新的合成途径。这些化合物的药物成分用于治疗患有精神疾病和/或与之相关的睡眠障碍的人咳嗽受体（尤其是抑郁症，焦虑症和ircadian周期障碍）以及成分生产程序。

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公开/公告号CO2019004756A2

专利类型
公开/公告日2019-05-21

原文格式PDF
申请/专利权人 ACHÉ LABORATÓRIOS FARMACÊUTICOS S.A.;
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申请/专利号CO20190004756
发明设计人 RUCH WERNECK GUIMARÃES CRISTIANO;FELYPE ZANETI DE AZEVEDO HATYLAS;MASCARELLO ALESSANDRA;WATANABE DA COSTA RENATA;FREIRE TORRES RUSSO VALTER;MANNOCHIO DE SOUZA RUSSO ELISA;
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申请日2019-05-09
分类号C07D235/26;A61K31/4184;A61P25/20;A61P25/22;A61P25/24;C07D235/28;
国家 CO
入库时间 2022-08-21 12:02:54

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