首页> 外国专利> CHEMICAL OR XEGOGENETIC HUMAN-MURINE ANTIBODY, HUMANIZED, HUMAN OR ITS CONNECTION FRAGMENT, EXPRESSION VECTOR, TRANSGENIC MICROORGANISM, METHOD FOR PREPARING ANTIBODY OR FRAGMENT OF COMPOSITION, COMPOSITION OF THE DYNOSIS, COMPOSITION OF THE COMPOSITION FOR TUMOR DIAGNOSIS AND USE OF TUMOR-BINDING ANTIGEN MOLECULA

CHEMICAL OR XEGOGENETIC HUMAN-MURINE ANTIBODY, HUMANIZED, HUMAN OR ITS CONNECTION FRAGMENT, EXPRESSION VECTOR, TRANSGENIC MICROORGANISM, METHOD FOR PREPARING ANTIBODY OR FRAGMENT OF COMPOSITION, COMPOSITION OF THE DYNOSIS, COMPOSITION OF THE COMPOSITION FOR TUMOR DIAGNOSIS AND USE OF TUMOR-BINDING ANTIGEN MOLECULA

机译：化学或异基因人类人鼠抗体，人源化，人类或其连接片段，表达载体，转基因微生物，制备抗体或片段的方法，肌张力的组成，组成成分的组成，组成和组成莫洛卡拉

页面导航

摘要
著录项
相似文献

摘要

human antibody or binding fragment thereof, antigen, polynucleotide, vector, host cell, method for preparing an antibody or immunoglobulin binding fragment or chain (s) thereof, antibody, immunoglobulin chain or binding fragment thereof , composition, uses of the antibody or binding fragment, an antigen, a polynucleotide, a vector, or a cell, and a tumor antigen binding molecule, methods for treating or preventing the progression of a tumor in a individual; to improve symptoms associated with a tumor; to diagnose or examine an individual for the presence of a tumor, or to determine the individual's risk of developing a tumor, to diagnose and / or treat a tumor-related disorder, and to molecularly clone an antibody; Diagnosis of a tumor New human tumor-specific antibodies are provided, as well as fragments, derivatives and variants that recognize the ny-es0-1 antigen associated with the tumor. furthermore, pharmaceutical compositions containing such antibodies and mimics thereof in the treatment of tumors are described.

机译：人抗体或其结合片段，抗原，多核苷酸，载体，宿主细胞，抗体或其免疫球蛋白结合片段或链的制备方法，抗体，免疫球蛋白链或其结合片段，抗体的组成，用途或结合片段，抗原，多核苷酸，载体或细胞以及肿瘤抗原结合分子，用于治疗或预防个体中肿瘤进展的方法;改善与肿瘤有关的症状;诊断或检查个体是否存在肿瘤，或确定个体发生肿瘤的风险，诊断和/或治疗与肿瘤相关的疾病，以及分子克隆抗体;肿瘤的诊断提供了新的人类肿瘤特异性抗体，以及识别与肿瘤相关的ny-es0-1抗原的片段，衍生物和变异体。此外，描述了用于治疗肿瘤的包含此类抗体及其模拟物的药物组合物。

著录项

公开/公告号BRPI0808940B1

专利类型
公开/公告日2019-10-08

原文格式PDF
申请/专利权人 UNIVERSITÄT ZÜRICH (UNIVERSITY OF ZURICH);
展开▼

申请/专利号BR2008PI08940
发明设计人 ALEXANDER KNUTH;ALFRED ZIPPELIUS;CHRISTOPH ESSLINGER;DIRK JAEGER;HOLGER MOCH;IRENE ABELA;NORBERT GOEBELS;ROGER M. D. NITSCH;SANDRA KUENZLE;
展开▼

申请日2008-03-13
分类号A61K39/395;A61P35;C07K16;C07K16/30;G01N33/53;
国家 BR
入库时间 2022-08-21 12:03:08

相似文献

专利
外文文献
中文文献