首页> 外国专利> UMBILICAL BLOOD COMPOSITION, AND METHODS FOR TREATING MALIGNA DISEASE OR BENIGN DISORDER ASSOCIATED WITH THE HEMOATOPOETIC SYSTEM AND PREPARING AN UMBILICAL BLOOD COMPOSITION

UMBILICAL BLOOD COMPOSITION, AND METHODS FOR TREATING MALIGNA DISEASE OR BENIGN DISORDER ASSOCIATED WITH THE HEMOATOPOETIC SYSTEM AND PREPARING AN UMBILICAL BLOOD COMPOSITION

机译:脐血成分,以及治疗与血液系统相关的马里格纳氏病或良性疾病并制备脐血成分的方法

摘要

umbilical cord blood composition, and methods for treating a malignant disease or benign disorder associated with the hemoatopoietic system and for preparing an umbilical cord blood composition the umbilical cord (ucb) blood compositions of the present invention comprise the unique characteristics to have plasma that is substantially depleted from the ucb unit and red blood cells (rbc) that are not depleted from the ucb unit. Said ucb units can be prepared by a process that combines plasma depletion with cryopreservation, selection, thawing, and / or transplantation of hematopoietic stem cells providing superior clinical outcome by maximizing cell recovery after processing and dose of infusion cells after thawing. Also provided are methods for treating a wide variety of malignant and benign diseases associated with the hemoatopoietic system by administering the ucb compositions of the present invention.
机译:脐带血组合物,以及用于治疗与造血系统相关的恶性疾病或良性疾病的方法以及制备脐带血组合物的方法,本发明的脐带血(ucb)血液组合物具有独特的特征,即具有实质上为血浆的血浆从ucb单位耗竭的血液和未从ucb单位耗竭的红细胞(rbc)。所述ucb单位可以通过将血浆消耗与冷冻保存,选择,解冻和/或移植造血干细胞相结合的方法来制备,所述方法通过最大化处理后的细胞回收率和解冻后的注入细胞剂量来提供优异的临床结果。还提供了通过施用本发明的ucb组合物来治疗与造血系统有关的多种恶性和良性疾病的方法。

著录项

  • 公开/公告号BRPI0610968A2

    专利类型

  • 公开/公告日2019-05-14

    原文格式PDF

  • 申请/专利权人 STEMCYTE INC.;

    申请/专利号BR2006PI10968

  • 发明设计人 ROBERT CHOW;

    申请日2006-06-02

  • 分类号A01N1/02;A61K35/12;A61K35/28;A61K35/51;C12N5/078;

  • 国家 BR

  • 入库时间 2022-08-21 12:03:12

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号