首页> 外国专利> a new hydrogel made of double cross-linked glycosaminoglycans, particularly cross-linked hyaluronic acid, chondroitin or chondroitin sulfate, with reversible bonds using boronic acid or boroxol derivatives leading to new benefits. double cross-linked glycosaminoglycans, one bond via two ether unions with one hydroxyl group of each of the two glycosaminoglycans and one bond via an alkoxyboronate ester anion formed between a grafted boronate hemiester to one of the glycosaminoglycans and a steel diol function. another glycosaminoglycan. the diol function may be a main chain diol function or a diol portion of a diol functional moiety grafted to another glycosaminoglycan.

a new hydrogel made of double cross-linked glycosaminoglycans, particularly cross-linked hyaluronic acid, chondroitin or chondroitin sulfate, with reversible bonds using boronic acid or boroxol derivatives leading to new benefits. double cross-linked glycosaminoglycans, one bond via two ether unions with one hydroxyl group of each of the two glycosaminoglycans and one bond via an alkoxyboronate ester anion formed between a grafted boronate hemiester to one of the glycosaminoglycans and a steel diol function. another glycosaminoglycan. the diol function may be a main chain diol function or a diol portion of a diol functional moiety grafted to another glycosaminoglycan.

机译:一种由双交联的糖胺聚糖,特别是交联的透明质酸,软骨素或硫酸软骨素制成的新型水凝胶,具有可逆键,使用硼酸或硼氧烷衍生物可带来新的好处。双交联的糖胺聚糖,一个通过两个醚键与两个糖胺聚糖中的每一个的一个羟基键合,一个通过在接枝的硼酸酯半酯与糖胺聚糖之一之间形成的烷氧基硼酸酯阴离子和一个钢二醇官能键合。另一个糖胺聚糖。二醇官能团可以是主链二醇官能团或接枝到另一糖胺聚糖上的二醇官能团部分的二醇部分。

摘要

a new hydrogel made of double cross-linked glycosaminoglycans, particularly cross-linked hyaluronic acid, chondroitin or chondroitin sulfate, with reversible bonds using boronic acid or boroxol derivatives leading to new benefits. double cross-linked glycosaminoglycans, one bond via two ether unions with one hydroxyl group of each of the two glycosaminoglycans and one bond via an alkoxyboronate ester anion formed between a grafted boronate hemiester to one of the glycosaminoglycans and a steel diol function. another glycosaminoglycan. the diol function may be a main chain diol function or a diol portion of a diol functional moiety grafted to another glycosaminoglycan.
机译:一种由双交联的糖胺聚糖,特别是交联的透明质酸,软骨素或硫酸软骨素制成的新型水凝胶,具有可逆键,使用硼酸或硼氧烷衍生物可带来新的好处。双交联的糖胺聚糖,一个通过两个醚键与两个糖胺聚糖中的每一个的一个羟基键合,一个通过在接枝的硼酸酯半酯与糖胺聚糖之一之间形成的烷氧基硼酸酯阴离子和一个钢二醇官能键合。另一个糖胺聚糖。二醇官能团可以是主链二醇官能团或接枝到另一糖胺聚糖上的二醇官能团部分的二醇部分。

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