首页> 外国专利> methods for diagnosis of preeclampsia, for assessing the severity of preeclampsia, and for preeclampsia monitoring, biomarker uses, adapted method kit, and adapted device for diagnosing whether a patient has preeclampsia

methods for diagnosis of preeclampsia, for assessing the severity of preeclampsia, and for preeclampsia monitoring, biomarker uses, adapted method kit, and adapted device for diagnosing whether a patient has preeclampsia

机译:诊断先兆子痫的方法,评估先兆子痫的严重性和先兆子痫的监测方法,生物标志物的使用,改良的方法试剂盒和改良的设备,用于诊断患者是否患有先兆子痫

摘要

The present invention relates to a method for diagnosing preeclampsia or a condition related to preeclampsia in a pregnant patient. The condition related to preeclampsia may be eclampsia, hellp syndrome or proteinuria. said method is based on measuring the amount of the igfbp-7 biomarker (insulin-like growth factor binding protein 7) in a patient sample and comparing the measured amount with a reference. Also encompassed by the present invention are methods for assessing the severity of preeclampsia or a condition related to preeclampsia and methods for monitoring a preeclampsia or condition related to preeclampsia in a pregnant patient. . The present invention further relates to the use of the igfbp-7 biomarker or an agent that specifically binds igfbp-7 in a patient sample for diagnosis, monitoring or evaluation of preeclampsia severity or a condition. related to preeclampsia. Finally, the present invention relates to a device adapted to perform the method of the present invention.
机译:诊断子痫前期或与子痫前期有关的病症的方法技术领域本发明涉及一种诊断子痫前期或与子痫前期有关的病症的方法。与先兆子痫有关的病状可能是子痫,地狱综合征或蛋白尿。所述方法基于测量患者样品中igfbp-7生物标志物(胰岛素样生长因子结合蛋白7)的量,并将测量的量与参考值进行比较。本发明还包括评估先兆子痫或与先兆子痫有关的病症的严重性的方法和监测妊娠患者的先兆子痫或与先兆子痫有关的病症的方法。 。本发明进一步涉及igfbp-7生物标志物或特异性结合igfbp-7的试剂在患者样品中用于诊断,监测或评估先兆子痫严重性或病症的用途。与先兆子痫有关。最后,本发明涉及一种适于执行本发明的方法的设备。

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