首页> 外国专利> TUNGSTATE TREATMENT OF THE DYSBIOSIS ASSOCIATED WITH GASTROINTESTINAL INFLAMMATION

TUNGSTATE TREATMENT OF THE DYSBIOSIS ASSOCIATED WITH GASTROINTESTINAL INFLAMMATION

机译:消化道消化不良相关的消化不良的钨酸盐处理

摘要

The present invention provides compositions of therapeutic agents and methods of use for reducing and/or treating gastrointestinal inflammation. In particular aspects, the tungstate salts described herein and pharmaceutical compositions thereof inhibit the activity of one or a plurality of anaerobic respiratory enzymes in facultative anaerobic bacteria such as, for example, Enterobacteriaceae, that can exacerbate inflammation. In particular embodiments, the present invention provides compositions of therapeutic agents for treating gastrointestinal inflammation, as well as methods for treating or preventing gut microbial imbalance due to an increase in the abundance of intestinal Enterobacteriaceae.
机译:本发明提供了用于减少和/或治疗胃肠道炎症的治疗剂组合物和使用方法。在特定方面,本文所述的钨酸盐及其药物组合物抑制兼性厌氧细菌(例如肠杆菌科)中一种或多种厌氧呼吸酶的活性,其可加剧炎症。在特定的实施方案中,本发明提供了用于治疗胃肠道炎症的治疗剂的组合物,以及用于治疗或预防由于肠道肠杆菌科细菌数量的增加而导致的肠道微生物失衡的方法。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号