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METHOD FOR PREPARING HYALURONIC ACID DERMAL FILLERS, DERMAL FILLERS OBTAINED THEREBY AND THEIR USE
METHOD FOR PREPARING HYALURONIC ACID DERMAL FILLERS, DERMAL FILLERS OBTAINED THEREBY AND THEIR USE
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机译:透明质酸皮肤填充剂的制备方法,由此获得的皮肤填充剂及其用途
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摘要
The present invention generally relates to the field of hyaluronic acid (HA) dermal fillers, and more specifically to methods for preparing crosslinked HA-based compositions in the form of a gel comprising high-temperature dialysis and/or crosslinking in the presence of phosphate and an alkaline metal halide salt. The present invention further relates to crosslinked HA-based gel compositions prepared by said methods and their use as dermal fillers in aesthetic applications such as wrinkle treatments.
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