首页> 外国专利> Inflammatory Disease Treatment Composition Including Anti-Myosin Regulatory Light-Chain Polypeptide Antibody

Inflammatory Disease Treatment Composition Including Anti-Myosin Regulatory Light-Chain Polypeptide Antibody

机译:包括抗肌球蛋白调节轻链多肽抗体的炎性疾病治疗组合物

摘要

Provided is a means for inhibiting a function of CD69, whereby allowing suppression of an inflammatory response. That is, provided are: a composition for treating an inflammatory disease which includes an antibody that specifically recognizes a myosin regulatory light chain polypeptide (hereinafter abbreviated as Myl), preferably Myl9, Myl12a, and Myl12b, and inhibits a result of an effect of coexistence of Myl with CD69; a method of treating an inflammatory disease, including administering, to a subject diagnosed as having an inflammatory disease, a therapeutically effective amount of the antibody; and a method of identifying a compound that inhibits a result of an effect of coexistence of Myl with CD69, and a method of identifying a candidate compound for treating an inflammatory disease, including selecting a compound that inhibits the result.
机译:提供了一种抑制CD69功能从而抑制炎症反应的手段。即,提供:用于治疗炎性疾病的组合物,其包含特异性识别肌球蛋白调节性轻链多肽(以下简称为Myl),优选为Myl9,Myl12a和Myl12b的抗体,并且抑制共存作用的结果。 Myl含CD69;一种治疗炎性疾病的方法,包括对诊断为患有炎性疾病的受试者给予治疗有效量的抗体;本发明提供了一种抑制Myl与CD69共存的结果的化合物的方法,以及一种用于鉴定治疗炎性疾病的候选化合物的方法,包括选择一种抑制该结果的化合物。

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号