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DNA METHYLATION SIGNATURES ASSOCIATED WITH CHILDHOOD TRAUMA AND METHODS INVOLVING SAME
DNA METHYLATION SIGNATURES ASSOCIATED WITH CHILDHOOD TRAUMA AND METHODS INVOLVING SAME
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机译：与儿童创伤有关的DNA甲基化特征及其涉及的方法
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摘要
A method includes obtaining a biological sample from an individual, extracting DNA from cells in the sample, measuring the degree of methylation of the extracted DNA at one or more specified loci, and identifying if at least one locus exhibits an alteration in methylation or a degree of methylation that is outside of a normal limit. The method may further include determining whether an individual was exposed to abuse and/or trauma. In some cases, the method further includes treating the individual with a therapy effective to reverse the differential methylation of the DNA.
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