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METHOD FOR DETERMINING THE RISK OF DEVELOPING ACUTE KIDNEY INJURY IN A HUMAN SUBJECT WITH ACUTE MYOCARDIAL INFARCTION AND INHIBITING SUCH DEVELOPMENT
METHOD FOR DETERMINING THE RISK OF DEVELOPING ACUTE KIDNEY INJURY IN A HUMAN SUBJECT WITH ACUTE MYOCARDIAL INFARCTION AND INHIBITING SUCH DEVELOPMENT
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机译：确定发生急性心肌梗塞并阻止这种发展的人的急性肾损伤的风险的方法
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摘要
A method for determining a human subject's risk of developing acute kidney injury (AKI) from acute myocardial infarction (AMI) includes: obtaining a blood sample; determining at least two miRNA expression levels therein, which are selected from miR-23a-3p, miR-24-3p, and miR-145-5p expression levels; calculating probability of developing AKI from AMI based on the at least two miRNA expression levels and a logistic regression model; comparing the probability with a predetermined standard; and determining that the human subject is at the risk of developing AKI when the probability is higher than the predetermined standard. A composition may be administered to the human subject for inhibiting development of AKI, if any.
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