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NON-HUMAN MODEL ANIMAL OF RETINAL VASCULAR DISEASE, METHOD FOR PRODUCING SAME, AND METHOD FOR SCREENING DRUG FOR TREATING OR PREVENTING RETINAL VASCULAR DISEASE
NON-HUMAN MODEL ANIMAL OF RETINAL VASCULAR DISEASE, METHOD FOR PRODUCING SAME, AND METHOD FOR SCREENING DRUG FOR TREATING OR PREVENTING RETINAL VASCULAR DISEASE
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机译：视网膜血管疾病的非人类模型动物，产生方法以及筛查药物以治疗或预防视网膜血管疾病的方法
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摘要
Provided are a non-human model animal of a retinal vascular disease that can favorably show symptoms similar to those of human retinal vascular diseases such as human diabetic retinopathy, and a method for producing the non-human model animal. In particular, provided are a non-human model animal that is suitable for establishing a method for treating, preventing, or diagnosing retinal edema, which causes highly impaired vision, and a method for producing the non-human model animal. A method for screening a drug for treating and preventing a retinal vascular disease, the method using a non-human model animal, is provided. Provided are a non-human model animal of a retinal vascular disease in which constitutively active Akt is expressed, a method for producing a non-human model animal of a retinal vascular disease in which constitutively active Akt is expressed, and a method for screening a drug for treating or preventing a retinal vascular disease.
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