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Method to manage raw genomic data in a privacy preserving manner in a biobank

机译:在生物库中以隐私保护方式管理原始基因组数据的方法

摘要

A method to manage raw genomic data (SAM/BAM files) in a privacy preserving manner in a biobank. By using order preserving encryption of the reads' positions, the method provides a requested range of nucleotides to a medical unit, without revealing the locations of the short reads (which include the requested nucleotides) to the biobank.;The method prevents the leakage of extra information in the short reads to the medical unit by masking the encrypted short reads at the biobank. That is, specific parts of the genomic data for which the medical unit is not authorized or the patient prefers to keep secret are masked at the biobank, without revealing any information to the biobank.
机译:一种在生物库中以隐私保护方式管理原始基因组数据(SAM / BAM文件)的方法。通过使用顺序来保留读取位置的加密,该方法可向医疗单位提供所需的核苷酸范围,而不会向生物库显示短读取的位置(包括所需的核苷酸)。通过在生物库中屏蔽加密的短读段,可以将短读段中的其他信息提供给医疗部门。即,在生物库中掩盖了基因组数据的特定部分,这些部分的基因组数据没有获得医疗单位的授权或患者更愿意保密,而不会向生物库透露任何信息。

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