首页> 外国专利> Pulsed ultrasound modulated optical tomography with increased optical/ultrasound pulse ratio

Pulsed ultrasound modulated optical tomography with increased optical/ultrasound pulse ratio

机译:具有增加的光学/超声脉冲比的脉冲超声调制光学层析成像

摘要

A system and method of performing ultrasound modulated optical tomography. Ultrasound is delivered into a target voxel in an anatomical structure, and sample light is delivered into the anatomical structure, whereby a portion of the sample light passing through the target voxel is scattered by the biological tissue as signal light, and a portion of the sample light not passing through the target voxel is scattered by the anatomical structure as background light. The ultrasound and sample light are pulsed in synchrony, such that only the signal light is frequency shifted by the ultrasound. Multiple pulses of the sample light are delivered into the anatomical structure for each pulse of the ultrasound delivered into the target voxel. Reference light is combined with the signal light and background light to generate an interference light pattern, which is sequentially modulated to generate different interference light patterns, which are detected.
机译:一种执行超声调制光学层析成像的系统和方法。超声波以解剖结构被输送到目标体素,并且样本光被输送到解剖结构中,从而穿过目标体素的一部分样品光被生物组织作为信号光散射,并且一部分样本未穿过目标体素的光被解剖结构散射为背景光。超声波和样本光是同步脉冲的,因此只有信号光会被超声波频移。对于传递到目标体素中的超声的每个脉冲,样品光的多个脉冲被传递到解剖结构中。参考光与信号光和背景光组合以产生干涉光图案,该干涉光图案被顺序调制以产生不同的干涉光图案,该干涉光图案被检测到。

著录项

  • 公开/公告号US10299682B1

    专利类型

  • 公开/公告日2019-05-28

    原文格式PDF

  • 申请/专利权人 HI LLC;

    申请/专利号US201715844398

  • 申请日2017-12-15

  • 分类号A61B5;G01N21/17;G01N21/45;A61B5/1455;

  • 国家 US

  • 入库时间 2022-08-21 12:14:22

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