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Methods for establishing a vedolizumab dosing regimen to treat patients with irritable bowel disease
Methods for establishing a vedolizumab dosing regimen to treat patients with irritable bowel disease
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机译：建立维多珠单抗给药方案以治疗肠易激惹疾病的方法
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摘要
The present invention provides methods for predicting whether an individual having inflammatory bowel disease (IBD) is likely to respond to vedolizumab treatment. Also provided are methods for predicting whether an individual with IBD such as Crohn's disease or ulcerative colitis will develop autoantibodies against vedolizumab. The present invention also provides a treatment regimen for an IBD patient which includes measuring the level of one or more predictive markers of response to vedolizumab prior to administering the anti-α4β7 integrin drug.
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