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Method for prediction of prognosis by human papillomavirus DNA integration pattern

机译:用人乳头瘤病毒DNA整合模式预测预后的方法

摘要

Provided is a method for analyzing the prognosis of cervical cancer according to the human papillomavirus (HPV) DNA integration pattern. The method of analyzing the prognosis of cervical cancer according to the human papillomavirus DNA integration pattern of the present invention enables an observation of the HPV DNA integration pattern with accuracy and convenience via in situ hybridization (ISH) compared to qPCR analysis. Since the prognosis of cervical cancer having the tumors with an episomal pattern and an integrated pattern can be significantly distinguished when the HPV DNA integration patterns are classified by the above method, the survival rate after radiotherapy of cervical cancer, and in particular invasive cervical cancer, can be more accurately analyzed.
机译:提供了一种根据人乳头瘤病毒(HPV)DNA整合模式分析宫颈癌预后的方法。与qPCR分析相比,根据本发明的人乳头瘤病毒DNA整合模式分析宫颈癌预后的方法使得能够通过原位杂交(ISH)准确且方便地观察HPV DNA整合模式。当通过上述方法对HPV DNA整合模式进行分类时,由于可以显着地区分具有游离型和整合型肿瘤的宫颈癌的预后,因此宫颈癌,尤其是浸润性宫颈癌的放疗后生存率,可以更准确地分析。

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