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Simple oxidative VLDL (VLDL susceptibility to oxidation) and oxidative oxidative LDL (LDL susceptibility to oxidation) determination method and apparatus for determining that the risk of myocardial infarction or cerebral infarction due to atherosclerosis is high
Simple oxidative VLDL (VLDL susceptibility to oxidation) and oxidative oxidative LDL (LDL susceptibility to oxidation) determination method and apparatus for determining that the risk of myocardial infarction or cerebral infarction due to atherosclerosis is high
[PROBLEMS] There is a person who cannot prevent the onset of myocardial infarction even if the LDL cholesterol level is lowered based on the arteriosclerotic myocardial infarction prevention guidelines (2017 edition) of the Japanese Atherosclerosis Society. It is an object of the present invention to provide a method for screening a person who is prone to suffer from myocardial infarction or cerebral infarction or a person who is difficult to cause by a simple blood test to determine that the risk of myocardial infarction or cerebral infarction is high. The present invention is a method in which collected serum / plasma is heated as it is, or a sample with or without the addition of a thiol inhibitor is heated (incubation) to a certain temperature, and small particles LDL and small particles before and after heating are heated. LDL cholesterol or small dense LDL cholesterol (sLDLc) is measured, and the results are compared with each other, and the increase amount is superior, for example, 1.5 times or the increase rate is superior, for example, 50% or more. And an indirect oxidizable VLDL and an oxidizable LDL measuring method, a measuring reagent and an apparatus for determining that the risk of cerebral infarction is higher. [Selection] Figure 2
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