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Use of early lung adenocarcinoma malignancy diagnostic markers focusing on epithelial-mesenchymal transition
Use of early lung adenocarcinoma malignancy diagnostic markers focusing on epithelial-mesenchymal transition
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机译：早期肺腺癌恶性诊断标志物的应用，侧重于上皮-间质转化
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摘要
PROBLEM TO BE SOLVED: To provide an inspection method using a malignancy diagnostic marker which is effective in predicting relapse/metastasis of early-stage pulmonary adenocarcinoma, and a kit thereof.SOLUTION: A method for inspecting malignancy of early-stage pulmonary adenocarcinoma regarding a sample derived from a subject includes detecting phosphorylation of at least one portion selected from a group consisting of 516-th tyrosine of TrkC, 1404-th tyrosine of TNS1, and 92-nd serine of SSFA2. An inspection kit of early-stage pulmonary adenocarcinoma includes at least one reagent selected from a group consisting of a reagent by which phosphorylation of 516-th tyrosine of TrkC can be detected, a reagent by which phosphorylation of 1404-th tyrosine of TNS1 can be detected, and a reagent by which phosphorylation of 92-nd serine of SSFA2 can be detected. There are also provided an antibody and a peptide.SELECTED DRAWING: Figure 5
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