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Isolation and culture technology of large intestine epithelial stem cells and large intestine epithelial transplantation technology using the same
Isolation and culture technology of large intestine epithelial stem cells and large intestine epithelial transplantation technology using the same
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机译:大肠上皮干细胞的分离培养技术及使用该技术的大肠上皮移植技术
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摘要
It is an object of the present invention to provide a culture medium for in vitro culture of a colorectal epithelial stem cell or the like, a method of in vitro culturing a colorectal epithelial stem cell or the like using the culture medium, a prophylactic or therapeutic agent for a bowel disease containing a colorectal epithelial stem cell or the like cultured by the method, a method of administrating, i.e., transplanting a colorectal epithelial stem cell or the like cultured by the method to a bowel disease patient, and a method of isolating a colorectal epithelial stem cell or the like. The culture medium for in vitro culture of a colorectal epithelial stem cell and/or a colorectal epithelial cell characteristically contains serum albumin, Wnt3a, and r-spondin-1.
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