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DIAGNOSTIC BIOMARKER OF ONSET RISK OF PREGNANCY DIABETES MELLITUS

机译:妊娠糖尿病发病风险的诊断生物标志物

摘要

To provide a biomarker for judgement of an onset risk of a pregnancy diabetes mellitus which is detected in a biological specimen collectable by a method having a relatively less burden on the pregnant woman who is a subject and capable of accurately judging whether or not the risk for developing a pregnancy diabetes mellitus is high by a pregnant woman at a relatively initial stage after the pregnancy.SOLUTION: It is possible to determine whether or not the content of ethanolamine or methionine in the urine collected from a pregnant woman who is not developing a pregnancy diabetes mellitus is low as compared with a subject who does not develop the pregnancy diabetes mellitus, and whether or not the pregnant woman incurs a risk of developing the pregnancy diabetes mellitus by analysing whether or not the content of 1,3-diphosphoglycerate, shikimate-3-phosphate or N-acetyl-L-alanine is high or low as compared with the subject.SELECTED DRAWING: None
机译:提供一种生物标志物,用于判断妊娠糖尿病的发病危险,该生物标志物是通过可对受检者的孕妇负担相对较小,并且能够准确地判断是否患有该疾病的风险的方法收集的生物标本中检测到的。解决方案:可以确定从未怀孕的孕妇那里收集的尿液中乙醇胺或蛋氨酸的含量是否很高与未患妊娠糖尿病的受试者相比,糖尿病的患病率低,并且通过分析1,3-二磷酸甘油酸,-草酸酯-的含量,孕妇是否有患妊娠糖尿病的风险。与受试者相比,3-磷酸或N-乙酰基-L-丙氨酸含量高或低。

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