首页> 外国专利> MOLDED TABLET WHICH CONTAINS AZILSARTAN OR SALT THEREOF AND AMLODIPINE OR SALT THEREOF AND MANUFACTURING METHOD THEREOF, AS WELL AS METHOD FOR IMPROVING STABILITY OF MOLDED TABLET WHICH CONTAINS AZILSARTAN OR SALT THEREOF AND AMLODIPINE OR SALT THEREOF

MOLDED TABLET WHICH CONTAINS AZILSARTAN OR SALT THEREOF AND AMLODIPINE OR SALT THEREOF AND MANUFACTURING METHOD THEREOF, AS WELL AS METHOD FOR IMPROVING STABILITY OF MOLDED TABLET WHICH CONTAINS AZILSARTAN OR SALT THEREOF AND AMLODIPINE OR SALT THEREOF

机译：含有氮杂沙丁胺醇或其盐和其其中的吗啡碱或其盐的模塑片剂及其制造方法，以及提高含有氮杂沙丁胺或其盐和其和三甲胺吡啶或其盐的模塑片剂的稳定性的方法

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摘要

PROBLEM TO BE SOLVED: To provide molded tablets containing azilsartan or salt thereof and amlodipine or salt thereof which is excellent in stability of both drugs of azilsartan or a salt thereof and amlodipine or a salt thereof, and production methods thereof, as well as to provide a method for improving stability of a molded tablet containing azilsartan or salt thereof and amlodipine or salt thereof.;SOLUTION: Provided is a molded tablet containing azilsartan or a salt thereof and amlodipine or a salt thereof, and a tablet containing amlodipine or a salt thereof, as well as a method for producing and improving stability of a molded tablet containing azilsartan or a salt thereof and amlodipine or a salt thereof, which comprises: adding an either of water or water-containing organic solvent in which a binder is dissolved to a mixture containing azilsartan or a salt thereof and amlodipine or a salt thereof to obtain wetting powders; and subjecting the wetting powders to compression molding.;SELECTED DRAWING: None;COPYRIGHT: (C)2019,JPO&INPIT

机译：解决的问题：提供包含阿齐沙坦或其盐和氨氯地平或其盐的两种药物的稳定性均优异的包含阿齐沙坦或其盐和氨氯地平或其盐的模制片剂及其生产方法，并提供解决方案：提供一种含有阿齐沙坦或其盐和氨氯地平或其盐的成型片剂和含有氨氯地平或其盐的片剂的方法。以及用于生产和改善包含阿齐沙坦或其盐和氨氯地平或其盐的模压片剂的稳定性的方法，其包括：将水或其中溶解有粘合剂的水性有机溶剂中的任一种添加到片剂中。含有阿齐沙坦或其盐和氨氯地平或其盐的混合物，得到湿润粉剂; ;选择的图纸：无;版权：（C）2019，JPO＆INPIT

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公开/公告号JP2019104726A

专利类型
公开/公告日2019-06-27

原文格式PDF
申请/专利权人 ELMED CO LTD;
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申请/专利号JP20180226380
发明设计人 SUGIURA DAISUKE;MORITA YUTAKA;HIRANO KANAKO;
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申请日2018-12-03
分类号A61K31/4422;A61P9/12;A61P43;A61K31/4245;A61K9/20;A61K47/14;A61K47/32;
国家 JP
入库时间 2022-08-21 12:24:04

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