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CURCUMIN-CONTAINING PREPARATIONS, AND METHOD FOR EVALUATING ABSORBENCY OR ELUTION THEREOF

机译：含姜黄素的制备及其吸收或洗脱的评估方法

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摘要

To provide curcumin-containing preparations enabling efficient intake of curcumin.SOLUTION: Provided is a curcumin-containing preparation which contains amorphous curcumin and substantially no crystalline curcumin, in which (a) the half-width is 68 or more and/or (b) T1 is 1.30 seconds or less, in the peak having the maximum intensity within the chemical shift range of 6.7 to 6.9 ppm in the chart ofH-NMR spectrum measured under the following conditions. Measurement condition measurement solvent: heavy water (DO);H resonant frequency: 600 MHz; temperature: 37°C; experimental method: Inversion Recovery method; and waiting time of Inversion Recovery method: 0.1 to 1.3 seconds.SELECTED DRAWING: None

机译：提供能够有效摄取姜黄素的含姜黄素的制剂。解决方案：提供一种含有无定形姜黄素而基本上没有结晶姜黄素的含姜黄素的制剂，其中（a）半角宽为68或更大和/或（b）在以下条件下测定的1 H-NMR谱图中，在6.7〜6.9ppm的化学位移范围内具有最大强度的峰的T1为1.30秒以下。 <测量条件>测量溶剂：重水（DO）; H共振频率：600 MHz;温度：37°C;实验方法：反转恢复法;反转恢复方法的等待时间：0.1到1.3秒。选定的绘制：无

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公开/公告号JP2019151584A

专利类型
公开/公告日2019-09-12

原文格式PDF
申请/专利权人 SANEI GEN FFI INC;OSAKA UNIV;
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申请/专利号JP20180037731
发明设计人 NAGANO KAZUYA;YOSHIDA TAKUYA;TOSAKA KAZUMA;TSUTSUMI YASUHISA;KINOSHITA YOSHITAKE;
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申请日2018-03-02
分类号A61K31/12;A61P3/06;A61P9/12;A61P3/10;A61P37/08;A61K9/20;A61K9/14;A61K47/32;A61K47/14;A61K47/26;G01N24;
国家 JP
入库时间 2022-08-21 12:25:36

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