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ANTIBODY FOR THE SPECIFIC DETECTION OF CAAP47/48 FRAGMENTS
ANTIBODY FOR THE SPECIFIC DETECTION OF CAAP47/48 FRAGMENTS
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机译：用于CAAP47 / 48片段特异性检测的抗体
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摘要
The present invention relates to an antibody that binds specifically to CAAP47/48 fragments, allowing for the highly specific detection of CAAP47/48 for diagnostic purposes.;The invention further relates to a vector and kit comprising said antibody. The antibody can be used for determining and/or differentially diagnosing a CAAP47/48 correlated disease. For example, the antibody according to the invention can be used for determining whether an infection is of bacterial or non-bacterial origin.;The present invention also relates to a method for determining in a patient whether an infection is of bacterial or non-bacterial origin using the antibody according to the invention. Said method comprises determining the concentration of CAAP47/48 in a sample that has been taken from said patient, and determining whether said patient suffers from an infection of bacterial or non-bacterial origin based on the concentration of CAAP47/48 and designating the infection as of bacterial or non-bacterial origin.;Another aspect of the present invention is a method of monitoring the treatment of a patient with an antimicrobial drug, comprising determining the level of CAAP47/48 in a sample taking from said patient by using the antibody according to the invention and evaluating the effect of treatment with said antimicrobial drug based on the comparison of the levels of CAAP47/48 to reference values and the level of CAAP47/48 at different time-points in the same patient.
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