首页> 外国专利> A METHOD FOR IDENTIFICATION OF LOW GRADE CERVICAL CYTOLOGY CASES LIKELY TO PROGRESS TO HIGH GRADE/CANCER

A METHOD FOR IDENTIFICATION OF LOW GRADE CERVICAL CYTOLOGY CASES LIKELY TO PROGRESS TO HIGH GRADE/CANCER

机译:识别低级宫颈细胞学病例的方法,有望发展为高级/癌症

摘要

The present invention provides a method of using Raman spectroscopy for identification of low grade cervical cytology cases likely to progress to high grade/cancer. The Applicant has found that high quality Raman spectra can be successfully acquired from morphologically normal appearing cells from negative, LSIL and HSIL Thinprep® specimens and different grades of cervical pre-cancer can be separated with good sensitivities and specificities. Raman spectroscopy can further identify different categories of the LSIL cases i.e., whether they are likely to regress to negative or progress to HSIL cytology.
机译:本发明提供了一种使用拉曼光谱法鉴定可能发展为高等级/癌症的低等级宫颈细胞学病例的方法。申请人发现,可以从阴性,LSIL和HSILThinprep®标本的形态正常出现的细胞中成功获得高质量的拉曼光谱,并且可以以良好的敏感性和特异性分离出不同等级的宫颈癌。拉曼光谱可以进一步确定LSIL病例的不同类别,即它们是否可能消退为阴性或进展为HSIL细胞学。

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