首页> 外国专利> METHODS FOR THE TREATMENT OF KAPOSI'S SARCOMA OR KSHV-INDUCED LYMPHOMA USING IMMUNOMODULATORY COMPOUNDS, AND USES OF BIOMARKERS

METHODS FOR THE TREATMENT OF KAPOSI'S SARCOMA OR KSHV-INDUCED LYMPHOMA USING IMMUNOMODULATORY COMPOUNDS, AND USES OF BIOMARKERS

机译：免疫调节性化合物治疗卡波西氏肉瘤或KSHV诱导的淋巴瘤的方法及生物标记物的用途

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摘要

Provided herein are uses of gene and protein biomarkers as a predictor of clinical sensitivity of Kaposi's sarcoma (KS) or Kaposi's sarcoma-associated herpesvirus (KSHV) induced lymphoma and patient response to treatment with an immunomodulatory compound. Further provided herein are methods for the treatment or management of Kaposi's sarcoma or KSHV-induced lymphoma with an immunomodulatory compound, alone or in combination with doxorubicin.

机译：本文提供了基因和蛋白质生物标志物作为卡波西氏肉瘤（KS）或卡波西氏肉瘤相关疱疹病毒（KSHV）诱导的淋巴瘤和患者对免疫调节化合物治疗的临床敏感性的临床预测指标的用途。本文还提供了单独或与阿霉素组合用免疫调节化合物治疗或管理卡波西氏肉瘤或KSHV诱导的淋巴瘤的方法。

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公开/公告号EP3313818A4

专利类型
公开/公告日2019-01-23

原文格式PDF
申请/专利权人 CELGENE CORPORATION;THE U.S.A. AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES;
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申请/专利号EP20160815375
发明设计人 YARCHOAN ROBERT;ZELDIS JEROME;POLIZZOTTO MARK;DAVIS DAVID;SERETI IRINI;ULDRICK THOMAS;WHITBY DENISE;KHETANI VIKRAM;
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申请日2016-06-24
分类号C07D209/48;A61K31/404;A61K45/06;C07D471/04;C07D473/34;A61P35;
国家 EP
入库时间 2022-08-21 12:27:45

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