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COATING LIQUID FOR MICRONEEDLES, MICRONEEDLE-COATING SUBSTANCE, AND MICRONEEDLE ARRAY

机译：微粉，微粉涂层物质和微粉阵列的涂料液

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摘要

To provide a composition of a coating liquid for microneedle which is optimal for coating a microneedle with a medicinal ingredient. The coating liquid for microneedle of the present invention is an aqueous solution containing, as essential components of a base, a water-soluble polysaccharide, a monosaccharide and/or a disaccharide and a surfactant, characterized in that a ratio of the water-soluble polysaccharide to the base is 2 to 60 mass%, and the hardness after being dried is 10 N or more. The coating liquid for microneedle may further contain a water-soluble polyalcohol, and preferably a monosaccharide and/or a disaccharide is 30 to 95 mass%, a surfactant is 0.05 to 5 mass%, and a water-soluble polyalcohol is 10 mass% or less in the base. As the water-soluble polysaccharide, hydroxypropyl cellulose, hyaluronic acid, or carboxymethyl cellulose is preferable.

机译：提供用于微针的涂布液的组合物，其对于用药物成分涂布微针是最佳的。本发明的微针用涂布液是含有水溶性多糖，单糖和/或二糖和表面活性剂作为碱的基本成分的水溶液，其特征在于，水溶性多糖的比例相对于基材的硬度为2〜60质量％，干燥后的硬度为10N以上。微针用涂布液可以进一步含有水溶性多元醇，优选单糖和/或二糖为30〜95质量％，表面活性剂为0.05〜5质量％，水溶性多元醇为10质量％或2质量％以上。在基地少。作为水溶性多糖，优选羟丙基纤维素，透明质酸或羧甲基纤维素。

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公开/公告号EP3412312A4

专利类型
公开/公告日2019-10-02

原文格式PDF
申请/专利权人 COSMED PHARMACEUTICAL CO. LTD.;
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申请/专利号EP20170747446
发明设计人 QUAN YING-SHU;SAITO MIO;KITAOKA SHOUTA;KAMIYAMA FUMIO;
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申请日2017-02-01
分类号A61K47/26;A61K9/08;A61K9/70;A61K47/10;A61K47/34;A61K47/36;A61M37;A61K39/12;
国家 EP
入库时间 2022-08-21 12:30:37

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