首页> 外国专利> ADJUVANTS FREE OF CYTOKINES FOR CELL CULTURE MEDIA, IN PARTICULAR FOR IN VITRO FERTILIZATION, OR FOR THE CULTIVATION OF FOLLICLES, MALE GERMINAL CELLS OR EMBRYOS

ADJUVANTS FREE OF CYTOKINES FOR CELL CULTURE MEDIA, IN PARTICULAR FOR IN VITRO FERTILIZATION, OR FOR THE CULTIVATION OF FOLLICLES, MALE GERMINAL CELLS OR EMBRYOS

机译:不含细胞因子的细胞培养介质,特别是体外受精或卵泡,男性生殖细胞或胚胎培养的助剂

摘要

The subject of the present invention is compositions which can be used as adjuvants for the in vitro culture of cells, characterized in that they comprise at least two compounds chosen from the group consisting of a zinc salt, inositol under any one of its stereoisomeric forms, carnitine or a carnitine derivative, melatonin or an analogue, cystine in one of its stereoisomeric forms or as a derivative, cysteamine or a cysteamine salt, said compositions being free of cytokines. The invention also relates to in vitro fertilization processes and processes for the maturation of follicles, male germ cells, or embryos using such culture medium adjuvants, as well as kits for the implementation of these methods. methods and comprising a aforementioned lyophilizate and an aqueous solution, containing the other constituents of said culture media.
机译:本发明的主题是可用作细胞体外培养的佐剂的组合物,其特征在于它们包含至少两种选自锌盐,肌醇的任何一种立体异构体形式的化合物,肉碱或肉碱衍生物,褪黑激素或类似物,其立体异构体形式之一或作为衍生物的半胱胺或半胱胺盐,所述组合物不含细胞因子。本发明还涉及使用这种培养基佐剂的体外受精过程和卵泡,雄性生殖细胞或胚胎的成熟过程,以及用于实施这些方法的试剂盒。包含上述冻干物和水溶液的方法,其包含所述培养基的其他成分。

著录项

  • 公开/公告号FR3065225A1

    专利类型

  • 公开/公告日2018-10-19

    原文格式PDF

  • 申请/专利权人 PATRICK CHOAY SAS;

    申请/专利号FR20170053233

  • 发明设计人 PATRICK CHOAY;MOHAMED BIDRI;

    申请日2017-04-12

  • 分类号C12N5/02;C12N5/071;C12N5/073;C12N5/075;C12N5/076;

  • 国家 FR

  • 入库时间 2022-08-21 12:32:52

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