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ADJUVANTS FREE OF CYTOKINES FOR CELL CULTURE MEDIA, IN PARTICULAR FOR IN VITRO FERTILIZATION, OR FOR THE CULTIVATION OF FOLLICLES, MALE GERMINAL CELLS OR EMBRYOS
ADJUVANTS FREE OF CYTOKINES FOR CELL CULTURE MEDIA, IN PARTICULAR FOR IN VITRO FERTILIZATION, OR FOR THE CULTIVATION OF FOLLICLES, MALE GERMINAL CELLS OR EMBRYOS
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机译:不含细胞因子的细胞培养介质,特别是体外受精或卵泡,男性生殖细胞或胚胎培养的助剂
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摘要
The subject of the present invention is compositions which can be used as adjuvants for the in vitro culture of cells, characterized in that they comprise at least two compounds chosen from the group consisting of a zinc salt, inositol under any one of its stereoisomeric forms, carnitine or a carnitine derivative, melatonin or an analogue, cystine in one of its stereoisomeric forms or as a derivative, cysteamine or a cysteamine salt, said compositions being free of cytokines. The invention also relates to in vitro fertilization processes and processes for the maturation of follicles, male germ cells, or embryos using such culture medium adjuvants, as well as kits for the implementation of these methods. methods and comprising a aforementioned lyophilizate and an aqueous solution, containing the other constituents of said culture media.
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