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A method for the manufacture of a contrast medium for the mr - spectroscopy
A method for the manufacture of a contrast medium for the mr - spectroscopy
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机译：一种用于磁共振波谱学的造影剂的制造方法
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摘要
It is a method for the manufacture of a contrast medium for the mr - spectroscopy, including the process steps.A) hydrogenating a connection with the general formula (i)in theR1, R2, R3 and r4 may be identical or different and h, a c1-C.6-Alkyl group, alkoxy group or ether group and can be halogen, r5 for a substituent selected from hydrogenable, in which x stands for the substrate,with h2-Gas, which with para - hydrogen (p-1H2) is enriched, is hydrogenated;B) transmitting the polarization to the radical x;C) subjecting the compound obtained from the hydrogenation of photolysis, in which the substrate is cleaved off;D) injection of the resulting contrast medium in the object to be investigated.With the method according to the invention, it is possible to use a biologically active substrate, the imaging process for the amplification of the signals is used, the current mirrors to the hyper, without any waste products form by chemical reactions, for example, salts, which in particular in the case of in vivo - investigations disturbances or side effects in the patient can cause.n="17"
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