;and ; ;which have increased stability in the manufacture of solid dosage forms for treatment of bacterial infections.;EFFECT: compounds have increased stability in the manufacture of solid dosage forms for treatment of bacterial infections.;11 cl, 12 dwg, 15 ex, 12 tbl"/> CRYSTALLINE PARTICLES FOR PREPARATION OF SOLID DOSAGE FORMS FOR TREATMENT OF BACTERIAL INFECTIONS, REACTION MIXTURE CONTAINING SUCH PARTICLES, AND PHARMACEUTICAL COMPOSITION FOR TREATING BACTERIAL INFECTIONS
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首页> 外国专利> CRYSTALLINE PARTICLES FOR PREPARATION OF SOLID DOSAGE FORMS FOR TREATMENT OF BACTERIAL INFECTIONS, REACTION MIXTURE CONTAINING SUCH PARTICLES, AND PHARMACEUTICAL COMPOSITION FOR TREATING BACTERIAL INFECTIONS

CRYSTALLINE PARTICLES FOR PREPARATION OF SOLID DOSAGE FORMS FOR TREATMENT OF BACTERIAL INFECTIONS, REACTION MIXTURE CONTAINING SUCH PARTICLES, AND PHARMACEUTICAL COMPOSITION FOR TREATING BACTERIAL INFECTIONS

机译：晶体颗粒，用于制备用于治疗细菌感染，包含此类颗粒的反应混合物以及用于治疗细菌感染的药物组合物的固体剂型

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FIELD: medicine; pharmaceuticals.;SUBSTANCE: crystalline particles are proposed containing (R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyl oxazolidin-2-one dihydrogen phosphate, X-ray diffraction patterns characterized by peaks at 14.7°, 15.2°, 16.6°, 20.3°, 26.8° and 28.2°, and also compositions on their basis, suitable for use in the pharmaceutical industry. New crystalline particles characterized by an average diameter of from 1.0 mcm to 44.0 mcm are proposed, content in addition to the main substance of water and at least one compound selected from: ; ;and ; ;which have increased stability in the manufacture of solid dosage forms for treatment of bacterial infections.;EFFECT: compounds have increased stability in the manufacture of solid dosage forms for treatment of bacterial infections.;11 cl, 12 dwg, 15 ex, 12 tbl
机译：领域：医学;药物：物质：建议包含（R）-3-（4-（2-（2-（2-甲基四唑-5-基）吡啶基-5-基）-3-氟苯基）-5-羟甲基恶唑烷-2-一种磷酸二氢盐，X射线衍射图谱，其特征在于在14.7°，15.2°，16.6°，20.3°，26.8°和28.2°处具有峰，以及基于它们的组合物，适用于制药工业。提出了一种新的结晶颗粒，其特征是平均直径为1.0mcm至44.0mcm，除水和至少一种选自以下物质的主要成分外，还含有其他成分： ;和 ;效果：化合物在制备用于治疗细菌感染的固体剂型中具有更高的稳定性。效果：化合物在制备用于治疗细菌感染的固体剂型中具有更高的稳定性。11 cl，12 dwg，15 ex，12 tbl

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