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首页> 外国专利> METHOD FOR PREDICTING RISK OF DEVELOPING MULTIOCULAR SCLEROSIS IN PATIENTS WITH SUBACUTE COURSE OF OPTIC NEURITIS

METHOD FOR PREDICTING RISK OF DEVELOPING MULTIOCULAR SCLEROSIS IN PATIENTS WITH SUBACUTE COURSE OF OPTIC NEURITIS

机译：预测视神经炎急性发作的多发性硬化症的风险的方法

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FIELD: medicine.;SUBSTANCE: invention is designed to predict the development of multiocular sclerosis (MS) in patients with subacute course of optic neuritis (ON). In serum, the level of optical density for antibodies of IgM class to the antigen of the retina is determined. Magnitude of peak latency and amplitude of the R100 visual evoked potentials (VEP), amplitude of N95 pattern-electroretinogram (PERG), photopic negative response to the conicus ERG (FNR). When the level of optical density for IgM class antibodies to retina S-antigen is equal and more than 0.15, extending of peak latency of R100 VEP at 20% or more, reducing the amplitude of N95 ERG and/or amplitude of FNR to 20% or more the development of multiocular sclerosis is predicted.;EFFECT: use of the invention makes it possible to provide specialized assistance in a timely manner in order to prevent the aggravation of the course of multiple sclerosis.;3 ex
机译：技术领域：本发明旨在预测患有亚急性视神经炎（ON）病程的多眼硬化症（MS）的发展。在血清中，确定针对视网膜抗原的IgM类抗体的光密度水平。峰值潜伏期的幅度和R100视觉诱发电位（VEP）的幅度，N95模式-视网膜电图（PERG）的幅度，对圆锥形ERG的明视负响应（FNR）。当针对视网膜S抗原的IgM类抗体的光密度水平等于或大于0.15时，R100 VEP的峰值潜伏期延长至20％或更多，从而将N95 ERG的幅度和/或FNR的幅度降低至20％效果：使用本发明可以及时提供专门的协助，以防止多发性硬化症病情加重。3 ex

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