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DESIGN SYNTHESIS AND APPLICATIONS OF UPCONVERSION NANOPARTICLES USING THE FIRST PRINCIPLES
DESIGN SYNTHESIS AND APPLICATIONS OF UPCONVERSION NANOPARTICLES USING THE FIRST PRINCIPLES
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机译:基于第一原理的上转换纳米粒子的设计合成及应用
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摘要
The present invention relates to a method for producing a compound of formula (I), which comprises at least one host selected from LiYF 4 , NaY, NaYF 4 , NaGdF 4 and CaF 3 ; At least one sensitizer selected from Sm 3+ , Nd 3+ , Dy 3+ , Ho 3+ and Yb 3+ doped to the host; And at least one activator selected from Er 3+ , Ho 3+ , Tm 3+ and Eu 3+ doped to the host. The upconverted nanoparticles of the present invention can be designed using first-principles calculations to absorb near-infrared wavelengths with stability. It is also possible to use such up-converted nanoparticles in combination with hyaluronic acid to utilize them in various places in the body having hyaluronic acid receptors, to provide hyaluronic acid-upturned nanoparticles capable of specifically targeting and maintaining body maintenance period and biocompatibility Lt; / RTI
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