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- Novel domestic-type methicillin-resistant Staphylococcus aureus strains and screening method for inhibiting biofilm formation

机译：-新型家用型耐甲氧西林金黄色葡萄球菌菌株及抑制生物膜形成的筛选方法

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摘要

The present invention relates to a methicillin-resistant Staphylococcus aureus (MRSA) 12KKPN53 strain (accession number: KCTC 13226BP) having high biofilm formation ability, a method for screening a biofilm formation inhibitor using the same, a composition for developing a biofilm formation inhibitor comprising the strain, and a kit. The methicillin-resistant Staphylococcus aureus (MRSA) strain deposited with the accession number KCTC 13226BP according to the present invention has remarkably excellent biofilm-forming ability as compared with other methicillin-resistant Staphylococcus aureus strains, and thus can be useful for screening a novel biofilm formation inhibitor. Therefore, the methicillin-resistant Staphylococcus aureus (MRSA) strain can be used to develop therapeutic agents for various clinical diseases caused by biofilm formation.

机译：具有高生物膜形成能力的耐甲氧西林金黄色葡萄球菌（MRSA）12KKPN53菌株（登录号：KCTC 13226BP），使用该菌株筛选生物膜形成抑制剂的方法，用于开发生物膜形成抑制剂的组合物菌株和试剂盒。与其他耐甲氧西林金黄色葡萄球菌菌株相比，本发明保藏号为KCTC 13226BP的耐甲氧西林金黄色葡萄球菌（MRSA）菌株具有非常优异的生物膜形成能力，因此可用于筛选新型生物膜。形成抑制剂。因此，耐甲氧西林的金黄色葡萄球菌（MRSA）菌株可用于开发针对由生物膜形成引起的各种临床疾病的治疗剂。

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公开/公告号KR101908411B1

专利类型
公开/公告日2018-10-17

原文格式PDF
申请/专利权人 REPUBLIC OF KOREA(ANIMAL AND PLANT QUARANTINE AGENCY);
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申请/专利号KR20170077984
发明设计人 MOON DONG CHAN;LIM SUK KYUNG;JANG GEUM CHAN;JUNG SUK CHAN;LEE HEE SOO;
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申请日2017-06-20
分类号C12N1/20;C12Q1/18;C12R1/445;
国家 KR
入库时间 2022-08-21 12:36:57

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