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A Method for promoting proliferation and osteogenic differentiation of Human Alveolar Bone-derived Mesenchymal Stem Cells and a composition therefor
A Method for promoting proliferation and osteogenic differentiation of Human Alveolar Bone-derived Mesenchymal Stem Cells and a composition therefor
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机译:一种促进人牙槽骨间充质干细胞增殖和成骨分化的方法及其组合物
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摘要
The present invention relates to a method for culturing alveolar bone-derived mesenchymal stem cells (ABMSCs) in α-minimal essential medium containing β-glycerophosphate and ascorbic acid, The cells were cultured under fluid shear stress during the incubation period, and after 4-6 days, the culture medium was collected to remove cell debris, filtered using a filter, and then cultured in a medium containing the harvested medium as an active ingredient The present invention provides a composition for alveolar bone-derived mesenchymal stem cell proliferation and osteogenic differentiation promotion. The composition of the present invention promotes alveolar bone-derived mesenchymal stem cell proliferation and osteogenesis differentiation, synergistically promotes differentiation and maturation of alveolar bone-derived mesenchymal stem cells, and induces osteoblast differentiation.
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