Marker for detecting Haliotis gigantean and method of detecting Haliotis gigantean using the same

• 1. 检测可流动物质样品中的生物标记物的存在的方法、用于检测可流动物质样品中的生物标记物的检测器组件及用于检测可流动物质样品中的生物标记物的存在的检测器单元 [P] . 中国专利： CN112424607A . 2021-02-26
• 2. 认知功能障碍疾病的生物标记物及使用该生物标记物的认知功能障碍疾病的检测方法 [P] . 中国专利： CN111426848A . 2020-07-17
• 3. Mircrosatellite marker for detecting Haliotis gigantean and method of detecting Haliotis gigantean using the same [P] . 韩国专利： KR20170122599A . 2017-11-06

  机译： 用于检测巨型霍洛特氏菌的微卫星标记和使用该标记的方法

• 4. Mircrosatellite marker for detecting Haliotis gigantean and method of detecting Haliotis gigantean using the same [P] . 韩国专利： KR101796306B1 . 2017-11-10

  机译： 用于检测巨型霍洛特氏菌的微卫星标记和使用该标记的方法

• 5. Single nucleotide polymorphism marker for detecting Haliotis gigantea and method of detecting Haliotis gigantea using the same [P] . 韩国专利： KR101743275B1 . 2017-06-02

  机译： 用于检测巨大假单胞菌的单核苷酸多态性标记物及其检测方法

• 1. Development and Characterization of Microsatellite Markers for the Pacific Abalone (Haliotis discus) via EST Database Mining [J] . ZHAN Aibin, BAO Zhenmin, WANG Mingling, 中国海洋大学学报（英文版） . 2008,第002期
• 2. Genetic variation of Chinese and Japanese wild Pacific abalone (Haliotis discus hannai) measured by microsatellite DNA markers [J] . LI Qi, KIJIMA Akihiro 海洋学报（英文版） . 2006,第004期
• 3. Morphometric Traits and Condition Indices in Artificially Induced Hybrids and Their Parental Species, Haliotis gigantean Gmelin (female) and H. discus discus Reeve (male) [J] . Genes and genomics . 2008,第2期
• 4. Molecular insights into a molluscan transferrin homolog identified from disk abalone (Haliotis discus discus) evidencing its detectable role in host antibacterial defense [J] . Herath H. M. L. P. B., Elvitigala Don Anushka Sandaruwan, Godahewa G. I., Developmental and Comparative Immunology: Ontogeny, Phylogeny, Aging: The Official Journal of the International Society of Developmental and Comparative Immunology . 2015,第1期
• 5. Virus-like particles detected in postlarvae of abalone (Haliotis diversicolor supertexta Lischke) potentially associated with mass mortalities [J] . Jing Zhou, Renjun Wang, Junpeng Cai African Journal of Microbiology Research . 2013,第16期
• 6. Augmented Reality Performance in Detecting Hardware Components Using Marker Based Tracking Method [C] . Siti Sendari, Desi Anggreani, Mahfud Jiono, International Conference on Vocational Education and Training . 2020
• 7. The influence of density-dependent aggregation characteristics on the population biology of benthic broadcast-spawning gastropods: Pink abalone (Haliotis corrugata), red abalone (Haliotis rufescens), and wavy turban snails (Megastraea undosa). [D] . Button, Cynthia Aileen. 2008
• 8. Identification of markers linked to disease-resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations. [O] . R W Michelmore, I Paran, R V Kesseli 1991
• 9. Virus-like particles detected in postlarvae of abalone (Haliotis diversicolor supertexta Lischke) potentially associated with mass mortalities [O] . Zhou Jing, Wang Renjun, Cai Junpeng 2013
• 10. Species in the Spotlight Priority Actions: 2016-2020, White Abalone ('Haliotis sorenseni'). [R] . 2016

• 1. 皱纹盘鲍(Haliotis discus hannai Ino)和杂色鲍(Haliotis diversicolor Reeve)遗传多样性的RAPD研究 [J] . 李太武 ,杨文新 ,宋林生 . 海洋与湖沼 . 2003,第004期
• 2. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 3. 岩扇贝(Crassadoma gigantean)新品种引进及产品加工展望 [J] . 邹建威 ,曹善茂 ,李晓雨 . 科技风 . 2019,第003期
• 4. 59/80R63无内胎全钢巨型工程机械子午线轮胎的设计 [C] . 黄振华 ,郭其焰 ,许志展 . 赛轮金宇杯第19届中国轮胎技术研讨会 . 2016
• 5. 基于微流控芯片和DNA编码探针的多元分析方法及其用于多肿瘤标记物同时检测研究 [A] . 谢林舜 . 2019