首页> 外国专利> Method for production of kaempferol-3-O--D-glucopyranosyl-14-O--D-glucopyranoside by cyclodextrin glucanotransferase and composition with kaempferol-3-O--D-glucopyranosyl-14-O--D-glucopyranoside therefrom

Method for production of kaempferol-3-O--D-glucopyranosyl-14-O--D-glucopyranoside by cyclodextrin glucanotransferase and composition with kaempferol-3-O--D-glucopyranosyl-14-O--D-glucopyranoside therefrom

机译：用环糊精葡糖基转移酶生产kaempferol-3-O-D-吡喃葡萄糖基-14-O-D-吡喃葡萄糖苷的方法和由其组成的kaempferol-3-O-D-吡喃葡萄糖基-14-O-D-吡喃葡萄糖苷

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摘要

The present invention can produce glycol-compounds of Astragalin with increased water solubility of 65 to 420 times higher than water solubility of conventional astragalin by glycoconversion of Astragalin through cyclodextrin glucanotransferase (CGTase). In addition, the glycol-compounds of Astragalin produced by method have remarkably improved aldose-reduction inhibiting effect, anti-inflammatory effect and antioxidative effect, compared to the conventional astragalin, thereby providing a composition for preventing or treating diabetic complications and an anti-inflammatory composition.

机译：本发明可以通过环糊精葡糖基转移酶（CGTase）将黄芪苷进行糖转化，从而制备出比常规黄芪苷的水溶性高65至420倍的黄芪醇二醇化合物。另外，与常规的黄芪素相比，通过该方法生产的黄芪素的二醇化合物具有显着改善的醛糖还原抑制作用，抗炎作用和抗氧化作用，从而提供了用于预防或治疗糖尿病并发症和抗炎的组合物。组成。

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公开/公告号KR20180105949A

专利类型
公开/公告日2018-10-01

原文格式PDF
申请/专利权人 INDUSTRY ACADEMIC COOPERATION FOUNDATION HALLYM UNIVERSITY;
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申请/专利号KR20170033309
发明设计人 SHIM JAE HOON;LIM SOON SUNG;CHOUNG WOO JAE;HWANG SEUNG HWAN;
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申请日2017-03-16
分类号C12P19/60;A23L33/10;A61K31/7048;
国家 KR
入库时间 2022-08-21 12:39:05

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