首页> 外国专利> -VEGF Novel anti-vascular endothelial growth factor antibody and composition for preventing or treating age-related macular degeneration comprising thereof

-VEGF Novel anti-vascular endothelial growth factor antibody and composition for preventing or treating age-related macular degeneration comprising thereof

机译:-VEGF新型抗血管内皮生长因子抗体和用于预防或治疗与年龄有关的黄斑变性的组合物

摘要

The present invention relates to a novel anti-vascular endothelial growth factor (VEGF) antibody and a composition for preventing or treating age-related macular degeneration including the novel anti-VEGF antibody as an effective component. The novel anti-VEGF antibody of the present invention is specifically bonded to a VEGF antigen protein, has an excellent bonding force and has an effect for inhibiting neovascularization and improving retinal function in a choroidal neovascularization mouse model, thereby being utilized as a pharmaceutical composition for preventing or treating age-related macular degeneration, a method for providing information for diagnosing the disease and a kit for diagnosing the disease.
机译:本发明涉及新型抗血管内皮生长因子(VEGF)抗体和用于预防或治疗年龄相关性黄斑变性的组合物,所述组合物包含新型抗VEGF抗体作为有效成分。本发明的新型抗VEGF抗体与VEGF抗原蛋白特异性结合,具有优异的结合力,并且在脉络膜新血管形成小鼠模型中具有抑制新血管形成和改善视网膜功能的作用,从而被用作药物组合物。预防或治疗与年龄有关的黄斑变性,提供用于诊断疾病的信息的方法和用于诊断疾病的试剂盒。

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