首页> 外国专利> Composition for hepatic arterial chemoembolization using human serum albumin nanoparticles carrying an antitumor agent and method preparing thereof

Composition for hepatic arterial chemoembolization using human serum albumin nanoparticles carrying an antitumor agent and method preparing thereof

机译：使用携带抗肿瘤剂的人血清白蛋白纳米粒子进行肝动脉化疗栓塞的组合物及其制备方法

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摘要

The purpose of the present invention is to dramatically increase effects of hepatic arterial chemoembolization by developing a human serum albumin-based nanoparticle as a bioprotein capable of effectively supporting adriamycin in place of adriamycin which is an anticancer agent used in the hepatic arterial chemoembolization. The adriamycin-supported human serum albumin nanoparticle not only intensively infiltrates drugs effectively into cells but also derives synergistic effects to induce long-term therapeutic effects by using continuous drug release effects from the particle.

机译：本发明的目的是通过开发人血清白蛋白基纳米颗粒作为能够有效支持阿霉素的生物蛋白来代替阿霉素，阿霉素是用于肝动脉化学栓塞的抗癌剂，从而显着提高肝动脉化学栓塞的效果。阿霉素支持的人血清白蛋白纳米颗粒不仅有效地将药物有效地渗透到细胞中，而且还通过使用来自颗粒的连续药物释放作用而产生协同作用，以诱导长期的治疗作用。

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公开/公告号KR20180034289A

专利类型
公开/公告日2018-04-04

原文格式PDF
申请/专利权人 SOGANG UNIVERSITY RESEARCH FOUNDATION;SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION;IMGT CO. LTD.;
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申请/专利号KR20170125169
发明设计人 KIM HYUN CHEOL;CHUNG JIN WOOK;JUNG EUN AH;
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申请日2017-09-27
分类号A61K49/14;A61K31/337;A61K31/396;A61K31/7068;A61K49/04;A61K49/10;
国家 KR
入库时间 2022-08-21 12:40:23

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