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TLR2 A TLR2 overexpressed animal model for atherosclerosis and a method of producing thereof

机译:TLR2动脉粥样硬化的TLR2过表达动物模型及其生产方法

摘要

The present invention relates to a TLR2-overexpressed atherosclerotic animal model and to a manufacturing method thereof. The animal model according to the present invention is capable of propagating with the TLR2 overexpression being maintained permanently, and inducing TLR2 overexpression tissue-specific only in a blood vessel region, and since the TLR2 overexpression can be controlled by convenience, it is expected that the TLR2-overexpressed atherosclerotic animal model contributes greatly to the research for treatment and prognosis of atherosclerotic disease.
机译:TLR2过表达的动脉粥样硬化动物模型及其制造方法技术领域本发明涉及TLR2过表达的动脉粥样硬化动物模型及其制造方法。根据本发明的动物模型能够在永久保持TLR2过表达的情况下进行繁殖,并且仅在血管区域中诱导组织特异性的TLR2过表达,并且由于可以方便地控制TLR2过表达,因此期望TLR2过表达的动脉粥样硬化动物模型为动脉粥样硬化疾病的治疗和预后研究做出了巨大贡献。

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