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METHOD AND KIT FOR SCREENING INDUCER OR INHIBITOR OF ENDOTHELIAL-TO-MESENCHYMAL TRANSITION BASED ON CELL PHENOTYPE
METHOD AND KIT FOR SCREENING INDUCER OR INHIBITOR OF ENDOTHELIAL-TO-MESENCHYMAL TRANSITION BASED ON CELL PHENOTYPE
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机译：基于细胞表型筛选内皮细胞向间充质转化的诱导剂或抑制剂的方法和试剂盒
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摘要
The present invention relates to a method and a kit for screening an endothelial cell migration inducer or an inhibitor based on a cell phenotype. The method and kit for screening for endothelial cell migration inducing agents or inhibitors based on the cell phenotype according to the present invention can be used for screening endothelial cells using natural products, small molecules, chemical substances or micro RNAs involved in the process of endothelial cell migration of vascular endothelial cells In screening for substances that induce or inhibit migration, it is possible to perform based on the phenotype of a cell without any separate process or condition, so that the involved substance can be screened more quickly, easily and clearly. In addition, by constructing a library of substances involved in the process of endothelial cell migration of vascular endothelial cells through the screening method, in vitro diagnosis, treatment, or prevention of related diseases caused by endothelial cell migration of the vascular endothelial cells And can be usefully used for.
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