首页> 外国专利> COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING TH1-MEDIATED IMMUNE DISEASE, TH17-MEDIATED IMMUNE DISEASE, OR TH2-MEDIATED IMMUNE DISEASE COMPRISING PEDIOCOCCUS PENTOSACEUS AS ACTIVE INGREDIENT

COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING TH1-MEDIATED IMMUNE DISEASE, TH17-MEDIATED IMMUNE DISEASE, OR TH2-MEDIATED IMMUNE DISEASE COMPRISING PEDIOCOCCUS PENTOSACEUS AS ACTIVE INGREDIENT

机译：预防，改善或治疗TH1介导的免疫疾病，TH17介导的免疫疾病或TH2介导的免疫疾病的成分，包括PEDIOCOCCUS PENTOSACEUS作为有效成分

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摘要

The present invention relates to a composition for preventing, ameliorating, or treating a Th1-mediated immune disease, a Th17-mediated immune disease, or a Th2-mediated immune disease, the composition comprising Pediococcus pentosaceus as an active ingredient. The Pediococcus pentosaceus of the present invention induces regulatory T cells; regulates the ratio of the immune tolerant cytokine (IL-10; anti-inflammatory cytokine) to the immune activating cytokine (IL-12); and effectively controls a Th1-mediated immune disease, a Th17-mediated immune disease or a Th2-mediated immune disease by reducing Th1-related cytokines, Th17-related cytokines and Th2-related cytokines in the production of immunoglobulin E (IgE) and immune hypersensitive response, and therefore has an advantage that can be used as an anti-allergic composition and an anti-inflammatory composition.

机译：本发明涉及用于预防，改善或治疗Th1介导的免疫疾病，Th17介导的免疫疾病或Th2介导的免疫疾病的组合物，该组合物包含戊糖小球菌（Pediococcus pentosaceus）作为活性成分。本发明的戊糖小球菌可诱导调节性T细胞。调节免疫耐受细胞因子（IL-10;抗炎细胞因子）与免疫激活细胞因子（IL-12）的比例;通过减少免疫球蛋白E（IgE）和免疫球蛋白生产中的Th1相关细胞因子，Th17相关细胞因子和Th2相关细胞因子，有效控制Th1介导的免疫疾病，Th17介导的免疫疾病或Th2介导的免疫疾病过敏反应，因此具有可以用作抗过敏组合物和消炎组合物的优点。

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公开/公告号WO2018034492A1

专利类型
公开/公告日2018-02-22

原文格式PDF
申请/专利权人 KOREA FOOD RESEARCH INSTITUTE;
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申请/专利号WO2017KR08903
发明设计人 LEE SO YOUNG;SHON DONG HWA;SHIN HEE SOON;JUNG SUN YOUNG;DO JEONG RYONG;KWON DA AE;BAE MIN JUNG;EOM JI EUN;
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申请日2017-08-16
分类号A61K35/74;A61K8/99;A61Q19;A23K10/16;A23L33/135;
国家 WO
入库时间 2022-08-21 12:45:36

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10. 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