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VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS
VARIABLE DOMAINS OF CAMELID HEAVY-CHAIN ANTIBODIES DIRECTED AGAINST GLIAL FIBRILLARY ACIDIC PROTEINS
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机译:胶质原纤维酸性蛋白定向的可变重链抗体域
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摘要
The present invention relates to the use of variable domains of camelid heavy-chain antibodies (VHH domains) di-rectedagainst an intracellular target and having an isoelectric point of at least8.5, for targeting said intracellular target or for thepreparation of a peptide vector. Particularly, it concerns VHH domainsdirected against a glial fibrillary acidic protein and usesthereof for preparing therapeutic or diagnostic agents.
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