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POLYMER IDENTIFICATION, COMPOSITIONAL ANALYSIS AND SEQUENCING, BASED ON PROPERTY COMPARISON

机译:基于性能比较的聚合物鉴定,组成分析和测序

摘要

A data structure, tangibly embodied in a computer computer-readable medium, representing a polymer of chemical units is disclosed. The data structure includes an identifier including a plurality of fields for storing values corresponding to properties of the polymer. In one embodiment, the fields are capable of storing binary values. The polymer may, for example, be a polysaccharide and the chemical units may be saccharides. A computer-implemented method for determining whether properties of a query sequence of chemical units match properties of a polymer of chemical units. The query sequence is represented by a first data structure, tangibly embodied in a computer-readable medium, including an identifier including a plurality of bit fields for storing values corresponding to properties of the query sequence. The polymer is represented by a second data structure, tangibly embodied in a computer-readable medium, including an identifier including a plurality of bit fields for storing values corresponding to properties of the polymer. The invention also relates to methods of sequencing polymers such as nucleic acids, polypeptides and polysaccharides and methods for identifying a polysaccharide-protein interaction. The invention also involves a notational system referred to as Property Encoded Nomenclature.
机译:公开了一种有形地体现在计算机计算机可读介质中的表示化学单元的聚合物的数据结构。该数据结构包括标识符,该标识符包括用于存储与聚合物的性质相对应的值的多个字段。在一个实施例中,这些字段能够存储二进制值。聚合物可以例如是多糖,并且化学单元可以是糖。一种用于确定化学单元查询序列的属性是否与化学单元的聚合物的属性匹配的计算机实现的方法。查询序列由有形地体现在计算机可读介质中的第一数据结构表示,该第一数据结构包括标识符,该标识符包括用于存储与查询序列的属性相对应的值的多个位字段。聚合物由有形地体现在计算机可读介质中的第二数据结构表示,该第二数据结构包括标识符,该标识符包括用于存储与聚合物的特性相对应的值的多个位字段。本发明还涉及对诸如核酸,多肽和多糖之类的聚合物进行测序的方法以及用于鉴定多糖-蛋白质相互作用的方法。本发明还涉及一种称为属性编码命名法的符号系统。

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