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Prediction of postpartum HELLP syndrome, postpartum eclampsia, or postpartum preeclampsia

机译:产后HELLP综合征,产后子痫或产后先兆子痫的预测

摘要

A procedure to predict the risk, for a female subject, of developing at least one adverse consequence, which is related to preeclampsia, after giving birth to a child, said procedure, comprising the stages of: a ) measure, in a first sample obtained from a female subject, with a pregnancy without notable events, before giving birth to the child, (i) the level of the biomarker sFlt-1 (tyrosine kinase similar to type 1 fms, soluble) or the level of the biomarker Endoglina, and (ii) the level of the biomarker PIGF (Placental Growth Factor), b) calculate the first ratio factor of the biomarker levels, as measured in stage a), c ) measure, in a second sample obtained from the aforementioned female subject, after giving birth to the child, the levels of biomarkers measured in stage a), d) calculate the second ratio factor of the levels measured in the stage c), and e) compare the second The relationship factor with the first relationship factor.
机译:预测女性受试者至少有一个与先兆子痫相关的不良后果的风险的方法,该方法在生完孩子后与先兆子痫有关,所述方法包括以下步骤:a)在获得的第一份样品中进行测量从一名没有明显事件怀孕的女性受试者生下孩子之前,(i)生物标志物sFlt-1(类似于1fms型酪氨酸激酶的酪氨酸激酶,可溶)的水平或生物标志物Endoglina的水平,以及(ii)生物标志物PIGF(胎盘生长因子)的水平,b)在从上述女性受试者获得的第二个样品中,计算在阶段a)中测量的生物标志物水平的第一比例因子,c)测量。生下孩子后,在阶段a),d)中测得的生物标志物水平计算出在阶段c)中测得的水平的第二比例因子,以及e)将第二个相关因子与第一个相关因子进行比较。

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