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Composition for use in the treatment of hypercholesterolaemia and in the prevention of cardiovascular diseases.

机译：用于治疗高胆固醇血症和预防心血管疾病的组合物。

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摘要

The invention relates to a synergistic composition of naturally occurring substances, which is particularly effective in the treatment of hypercholesterolemia. The composition of the invention comprises at least one substance having 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitory activity, a substance having cytochrome CYP7A1 expression increasing activity, a substance having inhibitory activity against the enzyme Acyl-CoA: cholesterol acyltransferase ACAT1 and ACAT2 isoforms, procyanidins, and optionally, coenzyme Q10 and phytosterols.

机译：本发明涉及天然存在的物质的协同组合物，其在治疗高胆固醇血症中特别有效。本发明的组合物包括至少一种具有3-羟基-3-甲基戊二酰辅酶A还原酶抑制活性的物质，具有细胞色素CYP7A1表达增加活性的物质，对酶Acyl-CoA具有抑制活性的物质：胆固醇酰基转移酶ACAT1和ACAT2亚型，原花青素和可选的辅酶Q10和植物甾醇。

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公开/公告号IT201700025666A1

专利类型
公开/公告日2018-09-08

原文格式PDF
申请/专利权人 NEILOS S.R.L.;
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申请/专利号IT201700025666
发明设计人 DI MAIO UMBERTO;
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申请日2017-03-08
分类号A61K31/12;A61K31/122;A61K31/353;A61K31/36;A61K31/366;A61K31/4525;A61K31/568;A61K31/575;A61K31/7034;A61K36/062;A61K36/15;A61K36/328;A61K36/67;A61K36/73;A61K36/87;A61K36/9066;A61K45/06;A61P3/06;A61P9/10;
国家 IT
入库时间 2022-08-21 12:49:07

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