首页> 外国专利> Method for assessing the risk of a person to develop dental caries as well as an analytic kit for determining the risk of a person to develop dental caries

Method for assessing the risk of a person to develop dental caries as well as an analytic kit for determining the risk of a person to develop dental caries

机译:评估人患龋齿的风险的方法以及用于确定人患龋齿的风险的分析套件

摘要

A method for assessing the risk of a person developing dental caries by analysis of a saliva sample, buccal scraping or soft tissue comprises measuring allelic phenotypes of acidic proline rich proteins or genotypes corresponding to said allelic phenotypes; grouping measured allelic phenotypes into P4a (Db, PIF, PRP12), P1 (ΡIF2, PRP12), P6 (Pa, PIF, PRP1, PRP2) saliva phenotypes; assigning a high, moderate or low risk to a person producing saliva of P4a, P6, or P1 phenotype, respectively. Also disclosed is a kit and amplification primers for use in the method.
机译:一种通过分析唾液样品,颊刮或软组织来评估人患龋齿的风险的方法,该方法包括:测量富含酸性脯氨酸的蛋白质的等位基因表型或与所述等位基因表型相对应的基因型。将测得的等位基因表型分为P4a(Db,PIF,PRP12),P1(PIF2,PRP12),P6(Pa,PIF,PRP1,PRP2)唾液表型;分别向产生P4a,P6或P1表型唾液的人分配高,中或低风险。还公开了用于该方法的试剂盒和扩增引物。

著录项

  • 公开/公告号SE539813C2

    专利类型

  • 公开/公告日2017-12-05

    原文格式PDF

  • 申请/专利权人 NICKLAS STRÖMBERG;

    申请/专利号SE20160000214

  • 发明设计人 NICKLAS STRÖMBERG;

    申请日2016-07-08

  • 分类号G01N33/68;A61K35/38;A61P1/02;C12Q1/68;

  • 国家 SE

  • 入库时间 2022-08-21 12:49:19

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