首页> 外国专利> METHOD FOR DETECTING GASTRIC POLYP AND GASTRIC CANCER USING GASTRIC POLYP AND GASTRIC CANCER SPECIFIC METHYLATION MARKER GENE

METHOD FOR DETECTING GASTRIC POLYP AND GASTRIC CANCER USING GASTRIC POLYP AND GASTRIC CANCER SPECIFIC METHYLATION MARKER GENE

机译:用胃息肉和胃癌特异性甲基化标记基因检测胃息肉和胃癌的方法

摘要

SDC2 (NM_002998, new Deccan 2, syndecan 2) of the present invention is related to the novelty teabag of coral polyp stomach function regulating described above as specific methylation biomarker gene, more specifically, making the diagnosing gastric cancer of degree of methylation by using in biomarker and in an early stage of the above damage in and by measuring. The present invention provides a kind of methods to make to methylate by the islands CpG in detection specific marker place and polyp of stomach, that information of diagnosing gastric cancer. In addition, making the use of methylation detecting method and diagnostic compositions, external member, and nucleic acid chip is of the invention, can during initial transfection step early detection diagnosis of gastric cancer be it is possible, it is more more accurate than conventional method, can rapidly diagnosis of gastric cancer this be useful.
机译:本发明的SDC2(NM_002998,新的Deccan 2,syndecan 2)涉及作为特异性甲基化生物标志物基因的上述珊瑚息肉胃功能调节的新颖茶袋,更具体地讲,通过使用SDC2来诊断甲基化程度的胃癌。生物标志物,并在上述损害的早期阶段通过测量。本发明提供了一种通过孤岛CpG在检测胃的特异性标志物部位和息肉中进行甲基化的方法,以诊断胃癌的信息。另外,利用甲基化检测方法和本发明的诊断组合物,外部构件和核酸芯片,可以在初始转染步骤中对胃癌进行早期检测诊断,比常规方法更准确,可以快速诊断胃癌这很有用。

著录项

  • 公开/公告号TR201810602T4

    专利类型

  • 公开/公告日2018-08-27

    原文格式PDF

  • 申请/专利权人 GENOMICTREE INC.;

    申请/专利号TR20180010602T

  • 发明设计人 SUNG HWAN AN;TAE JEONG OH;

    申请日2013-09-26

  • 分类号C12N15/11;C12Q1/68;

  • 国家 TR

  • 入库时间 2022-08-21 12:49:55

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