A formula compound (I),X1 is cr10r11 or NR7; X is n or Cr6; R1 is c1-3 tar or c1-3 halide; R2 is h, halogen, c1-3 tar, etc.; R4 is c1-3 tar or c1-3 halogen tar; these compounds are heterogeneous bicycle cycles. These compounds are enzyme inhibitors of fiber growth factor (FGFR4),She is involved in various physiological processes, such as angiography. He also mentioned a pharmaceutical composer These compounds can be used to treat diseases related to POPs 4, such as liver cancer, cervical cancer, multicellular tumor and so on.
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机译:式(I)的化合物,X1为cr10r11或NR7; X为n或Cr 6; R1是c1-3焦油或c1-3卤化物; R 2为h,卤素,c1-3焦油等。 R4为c1-3焦油或c1-3卤素焦油;这些化合物是异质自行车循环。这些化合物是纤维生长因子(FGFR4)的酶抑制剂,参与多种生理过程,例如血管造影。他还提到了药物作曲家。这些化合物可用于治疗与POPs 4相关的疾病,例如肝癌,子宫颈癌,多细胞肿瘤等。
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