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surface modified solid aggregate microparticles, injectable material, process for preparing surface modified solid aggregate microparticles, method for treating an eye disorder, and use of surface modified solid aggregate microparticles
surface modified solid aggregate microparticles, injectable material, process for preparing surface modified solid aggregate microparticles, method for treating an eye disorder, and use of surface modified solid aggregate microparticles
The present invention is a solid (e.g., non-porous) microparticle treated on the drug-loaded surface that aggregates in vivo to form a larger consolidated particle for medical therapy. In one embodiment, the particles are used for eye therapy. Processes for producing the surface treated microparticle and injectable formulations including the surface treated microparticle are also provided. when used in the eye, long-term compatible intraocular delivery can be achieved without disrupting vision and minimizing undesirable inflammatory responses.
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