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use of a polypeptide to effect immune signaling and / or affect intestinal barrier function and / or modular metabolic condition
use of a polypeptide to effect immune signaling and / or affect intestinal barrier function and / or modular metabolic condition
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机译:使用多肽来影响免疫信号和/或影响肠屏障功能和/或模块化代谢状况
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摘要
It has been found that an extracellular polypeptide derived from akkermansia municiphila is capable of modulating and / or promoting the function of the intestinal mucosal immune system and / or maintaining and / or restoring the metabolic condition and / or increasing the physical integrity of the intestinal mucosal barrier in a mammal. polypeptide or host cells comprising such polypeptide may be used to prevent and / or treat a variety of conditions that benefit from increased physical integrity of the intestinal mucosal barrier and / or improved function of the intestinal mucosal immune system and metabolic condition. .
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