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α-peptide immunogen construct, compositions, antibody and uses of a α-peptide immunogen construct or combination
α-peptide immunogen construct, compositions, antibody and uses of a α-peptide immunogen construct or combination
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机译：α肽免疫原构建体，组合物，抗体以及α肽免疫原构建体或组合的用途
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abstract the present disclosure is directed to individual peptide immunogen constructs, peptide compositions comprising these a peptide immunogen constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these a peptide immunogen constructs, with the individual peptide immunogen constructs having the n-terminus of the aß peptide as the b cell (b) epitopes linked through spacer residue (s) to heterologous t helper cell (th) epitopes derived from pathogen proteins that act together to stimulate the generation of highly specific antibodies directed against the n-terminus of the aß peptide offering protective immune responses to patients at risk for or with alzheimer's disease. alzheimer dementia prevention and immunotherapy peptide vaccine The present invention relates to individual α-immunogen peptide constructs, peptide compositions comprising these α-immunogen peptide constructs and mixtures thereof, pharmaceutical compositions including vaccine formulations comprising these α-immunogen peptide constructs, with the individual α-immunogen peptide constructs having the β-peptide n-terminus, such as cell b (b) epitopes linked via heterologous t helper cell epitope (th) spacer residue (s) pathogenic protein derivatives that act together to stimulate the production of highly specific antibodies directed against the ß-peptide n-terminal offering protective immune responses to patients at risk for or with Alzheimer's disease.
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